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Olpasiran May Still Show Heart-Risk Reduction Despite Novartis Miss, UBS Says","url":"https://stock-news.laohu8.com/highlight/detail?id=2666710603","media":"MT Newswires Live","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2666710603?lang=en_us&edition=fundamental","pubTime":"2026-09-09 01:09","pubTimestamp":1788887360,"startTime":"0","endTime":"0","summary":"Amgen's  experimental heart drug olpasiran may still show a meaningful reduction in major cardiovascular events, even after Novartis'  competing drug failed in a large study, UBS Securities said Monday in a report.Novartis' pelacarsen trial came up short overall, though UBS' analysis suggests the drug might have shown a modest benefit of 7% to 11% reduction in heart-attack-and-stroke risk among patients with very high levels of lipoprotein, a cholesterol-like particle linked to heart disease, the report said.Amgen's study focuses on an even higher-risk group, and olpasiran lowers lipoprotein to a greater degree than pelacarsen, UBS said. Amgen's trial also uses a different primary endpoint that excludes stroke, and taken together, these factors may help turn a small numerical benefit into a statistically significant result, potentially around a 15% reduction in major cardiovascular events, the report said.UBS maintained its buy rating on Amgen stock and its $440 price target.Amgen 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