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SPYRE THERAPEUTICS INC

90.60

+1.892.13%

盤後：90.600.00000.00%19:30 EDT

成交量：88.61萬

成交額：7,980.64萬

市值：79.89億

市盈率：-45.08

高：91.41

開：90.00

低：87.89

收：88.71

52周最高：110.18

52周最低：14.51

股本：8,817.38萬

流通股本：8,097.70萬

量比：0.88

換手率：1.09%

股息：- -

股息率：- -

每股收益(TTM):-2.0100

每股收益(LYR):-1.9755

淨資產收益率：-22.98%

總資產收益率：-19.81%

市淨率：8.37

市盈率(LYR):-45.86

資料載入中...

總覽公司新聞公告

Spyre Therapeutics旗下Spy003療法在第12周實現20%臨床緩解率及30%內鏡改善率

BUZZ——美國股市動態-Semtech、唐納森、Meta

Spyre股價下跌，因關節炎藥物未達研發目標

Spyre Therapeutics盤前股價重挫12.4% 實驗性藥物未達類風濕關節炎單藥治療開發門檻

Spyre Therapeutics公司——療效幅度未達公司預設目標，類風濕關節炎候選藥物SPY072單藥療法開發優先級或將調整

Spyre Therapeutics公司：Spy072聯合Il17-a/F治療化膿性汗腺炎（HS）預計於2027年末或2028年初啓動

Spyre Therapeutics——Spy072在多項終點指標上較安慰劑展現統計學顯著優勢

Spyre Therapeutics公布Spy072 Skyway二期試驗類風濕關節炎亞研究頂線結果

美國研究綜述-Accendra Health、Celestica、Sionna Therapeutics

Spyre Therapeutics推出Spy772項目，啓動化膿性汗腺炎SkyLight二期臨床試驗

異動解讀｜Spyre Therapeutics盤中上漲11.41%，報104.42美元

異動解讀｜Spyre Therapeutics盤中上漲5.02%，報93.505美元

異動解讀｜SPYRE THERAPEUTICS盤前下跌5.04%，董事減持持續施壓股價

異動解讀｜Spyre Therapeutics盤中下跌14.76%，董事減持引發市場關注

異動解讀｜SPYRE THERAPEUTICS盤前下跌10.83%，報86.54美元

異動解讀｜SPYRE THERAPEUTICS夜盤下跌7.91%，報89.37美元

異動解讀｜SPYRE THERAPEUTICS盤後上漲8.19%，報105.0美元

Spyre稱，其腸道疾病藥物在中期試驗中顯示出減輕炎症的效果

Spyre Therapeutics：二十名受試者出現治療引發不良事件；兩例嚴重，均與藥物無關

SPYRE THERAPEUTICS：Spy002在第12周實現33%臨床緩解與42%內鏡改善

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Therapeutics股价在盘前交易时段大幅下跌12.4%，此前该公司宣布其一款实验性药物未能达到类风湿关节炎单药治疗开发所需的疗效阈值。这一消息令市场投资者颇感意外，引发对该生物科技公司研发管线前景的重新评估。受此利空冲击，该股在常规交易开始前即遭遇显著抛售压力，反映出市场对候选药物临床价值的疑虑正在加深。分析人士指出，未能跨越预设的疗效门槛意味着该药物作为单一疗法的开发路径将面临重大调整，公司或需重新考量其战略布局。投资者正密切关注公司后续的研发决策及可能的替代方案。","market":"us","thumbnail":"","type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"zh","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-2","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BK4139","SYRE","LFSC"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"1158063890","title":"Spyre 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Therapeutics公司近日披露，其类风湿关节炎在研药物SPY072在临床试验中展现的疗效幅度未能达到公司预先设定的目标阈值。这一结果意味着，该公司此前规划的单药疗法开发路径——即将SPY072作为独立治疗方案推进的优先策略——如今面临重新审视与调整的现实压力。","market":"us","thumbnail":"","type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"zh","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":null,"news_tag":"dataReport","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["LFSC","SYRE","BK4139"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"1107207144","title":"Spyre Therapeutics公司：Spy072聯合Il17-a/F治療化膿性汗腺炎（HS）預計於2027年末或2028年初啓動","url":"https://stock-news.laohu8.com/highlight/detail?id=1107207144","media":"美股速递","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/1107207144?lang=zh_tw&edition=fundamental","pubTime":"2026-08-26 04:02","pubTimestamp":1787688130,"startTime":"0","endTime":"0","summary":"Spyre Therapeutics Inc宣布，其候选药物Spy072与Il17-a/F联合疗法用于治疗化脓性汗腺炎（HS）的计划，预计将在2027年末或2028年初推进。这一时间表标志着该公司在炎症性疾病领域管线布局的重要节点，也反映出其对该联合方案临床开发节奏的审慎把控。","market":"us","thumbnail":"","type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"zh","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BK4139","SYRE","LFSC"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"1157101849","title":"Spyre Therapeutics——Spy072在多項終點指標上較安慰劑展現統計學顯著優勢","url":"https://stock-news.laohu8.com/highlight/detail?id=1157101849","media":"美股速递","labels":["dataReport"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/1157101849?lang=zh_tw&edition=fundamental","pubTime":"2026-08-26 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Therapeutics","url":"https://stock-news.laohu8.com/highlight/detail?id=2658998788","media":"路透中文","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2658998788?lang=zh_tw&edition=fundamental","pubTime":"2026-08-11 16:11","pubTimestamp":1786435905,"startTime":"0","endTime":"0","summary":"美国研究综述-Accendra Health、Celestica、Sionna Therapeutics路透8月11日-周二，华尔街证券分析师下调了多家在美国上市公司的评级和目标股价，其中包括Accendra Health、Celestica和Sionna 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Therapeutics推出Spy772項目，啓動化膿性汗腺炎SkyLight二期臨床試驗","url":"https://stock-news.laohu8.com/highlight/detail?id=1150250995","media":"美股速递","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/1150250995?lang=zh_tw&edition=fundamental","pubTime":"2026-08-10 20:01","pubTimestamp":1786363318,"startTime":"0","endTime":"0","summary":"Spyre Therapeutics（股票代码：SYRE）正式宣布，其全新研发项目Spy772已启动，并同步开启针对化脓性汗腺炎（Hidradenitis Suppurativa）的SkyLight二期临床试验。这一消息标志着公司在炎症性疾病治疗领域迈出关键一步。","market":"us","thumbnail":"","type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"zh","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["SYRE","BK4139","LFSC"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"1177727349","title":"異動解讀｜Spyre Therapeutics盤中上漲11.41%，報104.42美元","url":"https://stock-news.laohu8.com/highlight/detail?id=1177727349","media":"行情直击","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/1177727349?lang=zh_tw&edition=fundamental","pubTime":"2026-07-15 00:01","pubTimestamp":1784044892,"startTime":"0","endTime":"0","summary":"7月15日，Spyre Therapeutics盘中上涨11.41%，报104.42美元/股，成交额7429.81万美元。Spyre Therapeutics所在的生物科技行业中，个股表现分化，其中Nextcure Inc.涨213.3%，渤健公司跌8.42%，艾伯维公司跌1.24%，Shuttle Pharmaceuticals Inc涨31.42%，吉利德科学跌0.49%。Spyre Therapeutics是一家临床阶段生物技术公司，致力于通过结合同类最佳的抗体工程、合理的治疗组合以及精准医疗方法，开发下一代炎症性肠病产品，管线涵盖针对α4β7、TL1A和IL-23的延长半衰期抗体。","market":"hk","thumbnail":"","type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"zh","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["SYRE"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"1193512223","title":"異動解讀｜Spyre Therapeutics盤中上漲5.02%，報93.505美元","url":"https://stock-news.laohu8.com/highlight/detail?id=1193512223","media":"行情直击","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/1193512223?lang=zh_tw&edition=fundamental","pubTime":"2026-07-08 00:15","pubTimestamp":1783440956,"startTime":"0","endTime":"0","summary":"7月8日，Spyre Therapeutics盘中上涨5.02%，报93.505美元/股，成交额3902.22万美元。Spyre Therapeutics所在的生物科技行业中，个股中，福泰制药跌1.11%，艾伯维公司涨0.99%，吉利德科学涨3.70%，Moderna跌3.34%，安进涨0.46%。Spyre Therapeutics是一家临床阶段生物技术公司，旨在通过结合同类最佳的抗体工程、合理的治疗组合以及精准医疗方法，创造下一代炎症性肠病产品，产品线包括针对α4β7、TL1A和IL-23的延长半衰期抗体。","market":"us","thumbnail":"","type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"zh","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["SYRE"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"1121929272","title":"異動解讀｜SPYRE THERAPEUTICS盤前下跌5.04%，董事減持持續施壓股價","url":"https://stock-news.laohu8.com/highlight/detail?id=1121929272","media":"行情直击","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/1121929272?lang=zh_tw&edition=fundamental","pubTime":"2026-06-25 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Therapeutics是一家专注于炎症性肠病的生物技术公司，产品线包括针对α4β7、TL1A和IL-23的延长半衰期抗体，当前市净率约12.39倍，总市值约83亿美元。","market":"hk","thumbnail":"","type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"zh","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":null,"news_tag":"shareholding","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["SYRE"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"1134617087","title":"異動解讀｜SPYRE THERAPEUTICS盤前下跌10.83%，報86.54美元","url":"https://stock-news.laohu8.com/highlight/detail?id=1134617087","media":"行情直击","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/1134617087?lang=zh_tw&edition=fundamental","pubTime":"2026-06-24 16:02","pubTimestamp":1782288144,"startTime":"0","endTime":"0","summary":"6月24日，SPYRE THERAPEUTICS盘前下跌10.83%，报86.54美元/股，成交额1.75万美元。SPYRE 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THERAPEUTICS盤後上漲8.19%，報105.0美元","url":"https://stock-news.laohu8.com/highlight/detail?id=1121301590","media":"行情直击","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/1121301590?lang=zh_tw&edition=fundamental","pubTime":"2026-06-24 04:41","pubTimestamp":1782247295,"startTime":"0","endTime":"0","summary":"6月23日，SPYRE THERAPEUTICS盘后上涨8.19%，报105.0美元/股，成交额411.19万美元。SPYRE THERAPEUTICS所在的生物科技行业中，个股表现分化，艾伯维公司跌0.22%，Apogee Therapeutics跌0.14%，吉利德科学涨0.32%，再生元制药公司跌0.01%，安进跌0.58%。其产品线包括针对α4β7、TL1A和IL-23的延长半衰期抗体。（以上内容均基于市场公开消息，由程序或算法智能生成，仅作为股价异动提醒，不作为投资建议或交易依据。","market":"us","thumbnail":"","type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"zh","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["SYRE"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"2643203701","title":"Spyre稱，其腸道疾病藥物在中期試驗中顯示出減輕炎症的效果","url":"https://stock-news.laohu8.com/highlight/detail?id=2643203701","media":"路透中文","labels":["dataReport"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2643203701?lang=zh_tw&edition=fundamental","pubTime":"2026-06-15 20:26","pubTimestamp":1781526419,"startTime":"0","endTime":"0","summary":"Spyre称，其肠道疾病药物在中期试验中显示出减轻炎症的效果路透6月15日 - Spyre Therapeutics周一表示，其一款用于治疗肠道疾病的试验性药物在中期临床试验中达到了主要目标，即显著降低了疾病严重程度。次要结果显示，33%的患者达到了临床缓解，而42%的患者在内镜检查中显示出改善，这意味着通过内窥镜检查时，结肠的炎症看起来减轻了。Spyre补充道，SPY002耐受性良好，其安全性特征与其他针对TL1A的药物一致。","market":"hk","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"zh","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20260615:nL4T42N14D:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"dataReport","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BK4139","SYRE"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"1132100150","title":"Spyre Therapeutics：二十名受試者出現治療引發不良事件；兩例嚴重，均與藥物無關","url":"https://stock-news.laohu8.com/highlight/detail?id=1132100150","media":"美股速递","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/1132100150?lang=zh_tw&edition=fundamental","pubTime":"2026-06-15 20:03","pubTimestamp":1781525007,"startTime":"0","endTime":"0","summary":"Spyre Therapeutics公布了一项临床试验的更新数据，显示有二十名受试者出现了治疗引发的不良事件。其中，两例被评估为严重级别，但经过分析，这些严重事件均被判定与试验药物本身无关。","market":"us","thumbnail":"","type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"zh","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["SYRE","BK4139"],"isVideo":false,"video":null,"gpt_icon":0},{"id":"1107639416","title":"SPYRE THERAPEUTICS：Spy002在第12周實現33%臨床緩解與42%內鏡改善","url":"https://stock-news.laohu8.com/highlight/detail?id=1107639416","media":"美股速递","labels":["dataReport"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/1107639416?lang=zh_tw&edition=fundamental","pubTime":"2026-06-15 20:02","pubTimestamp":1781524958,"startTime":"0","endTime":"0","summary":"SPYRE THERAPEUTICS公司宣布，其候选药物Spy002在治疗第12周时取得了令人鼓舞的临床数据。\n结果显示，接受治疗的患者中有33%达到了临床缓解的标准。同时，内镜检查评估显示，42%的患者实现了内镜下病情的显著改善。\n这些中期数据为该药物的后续开发提供了积极信号。","market":"us","thumbnail":"","type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"zh","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"dataReport","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BK4139","SYRE"],"isVideo":false,"video":null,"gpt_icon":0}],"pageSize":20,"totalPage":3,"pageCount":1,"totalSize":43,"code":"91000000","status":"200"}]}}